Zhang F, Zhu X, Han D, Wang H, Wang L. (1999). Clinical study of capsaicin in the treatment of allergic rhinitis. Lin Chuang Er Bi Yan Hou Ke Za Zhi. Nov; 13(11): 499-500.
Abstract
OBJECTIVE
To study the clinical effect of capsaicin of nasal administration in 100 cases of allergic rhinitis.
METHODS
Capsaicin was applied by nostril, once 5 days and 5 times as a therapeutic course. Acidophil were measured and nasal airflow resistance was analysed before and after capsaicin therapy.
RESULT
It showed that nasal symptoms of patients were obviously relieved and 94% of the cases in the measure of acidophil changed to negative from positive. Moreover, capsaicin induced decrease in nasal airflow resistance from (0.6272 +/- 0.3534) kPa.s/L before therapy to (0.4057 +/- 0.2419) kPa.s/L after therapy (P < 0.001). Ninety cases of 100 patients were followed up one year; the total effective rate was 89%.
CONCLUSION
Our study suggests that capsaicin possessed remarkable effects in the treatment of allergic rhinitis; analyses of nasal airflow resistance may be used as one of the objective guideline in the determinant of therapeutic effects.
